Christopher D. Richardson is Professor, Department of Microbiology & Immunology, Department of Pediatrics, Dalhousie University, Canada. Dr. Chris Richardson is a molecular virologist with 35 years of experience working with a variety of viruses. He earned his PhD at the University of British Columbia and did postdoctoral work at The Rockefeller University and the National Institutes of Health (Bethesda, USA). He previously held faculty positions at the National Research Council of Canada, McGill University, and the University of Toronto.

Nicholas H. Acheson is Emeritus Professor of Microbiology & Immunology at McGill University, Quebec, Canada. He earned his PhD from The Rockefeller University and was a postdoctoral fellow at the Swiss Institute for Experimental Cancer Research (Lausanne) and Institut Pasteur (Paris). He carried out research on Semliki Forest virus and mouse polyomavirus, and taught a virology course for advanced undergraduate students at McGill University.

Section I: Introduction to Virology

1. Introduction to Virology 2
Nicholas H. Acheson, McGill University
Christopher D. Richardson, Dalhousie University

2. Virus Structure and Assembly 19
Stephen C. Harrison, Harvard University

3. Virus Classification: The World of Viruses 32
Nicholas H. Acheson, McGill University
Christopher D. Richardson, Dalhousie University

4. Virus Entry 47
Ari Helenius, Swiss Federal Institute of Technology, Zurich

Section II: Viruses of Bacteria and Archaea

5. Single-Stranded RNA Bacteriophages 60
Jan van Duin, University of Leiden
Karthik Chamakura, Armata Pharmaceuticals, Inc., Los Angeles
Ryland Young, Texas A&M University

6. Microviruses 74
Bentley A. Fane, University of Arizona
Aaron P. Roznowski, University of Arizona

7. Bacteriophage T7 84
William C. Summers, Yale University
Ian J. Molineux, University of Texas, Austin

8. Bacteriophage T4 94
Deborah M. Hinton, National Institutes of Health, Bethesda
Eric S. Miller, North Carolina State University

9. Bacteriophage Lambda 110
Michael Feiss, University of Iowa

10. Viruses of Archaea 123
David Prangishvili, Institut Pasteur, Paris Mart Krupovic, Institut Pasteur, Paris

Section III: Positive-Strand RNA Animal Viruses

11. Picornaviruses 140
Bert L. Semler, University of California, Irvine

12. Flaviviruses 152
Richard Kuhn, Purdue University
Shelton Bradrick, Trudeau Institute, New York

13. Hepaciviruses 164
John Lok Man Law, Memorial University of Newfoundland
Michael Houghton, University of Alberta

14. Togaviruses and Rubella Virus 178
Anil Kumar, University of Saskatchewan
Milton Schlesinger, Washington University, St. Louis
Sondra Schlesinger, Washington University, St. Louis
Tom C. Hobman, University of Alberta

15. Coronaviruses 192
Marc Desforges, Ste. Justine Hospital, Université de Montréal
Pierre Talbot, Institut Armand-Frappier
Mark Denison, Vanderbilt University

Section IV: Negative-Strand and Double-Stranded RNA Animal Viruses

16. Paramyxoviruses and Pneumoviruses 210
Nicholas H. Acheson, McGill University
Daniel Kolakofsky, University of Geneva
Laurent Roux, University of Geneva
Christopher D. Richardson, Dalhousie University

17. Rhabdoviruses 226
Valery Grdzelishvili, University of North Carolina, Charlotte
Cassandra A. Catacalos, University of North Carolina, Charlotte

18. Filoviruses 237
Heinz Feldmann, Rocky Mountain Laboratories, Montana
Hans-Dieter Klenk, University of Marburg
Nicholas H. Acheson, McGill University
Angela Rasmussen, University of Saskatchewan

19. Bunyaviruses 251
Richard M. Elliott, University of Glasgow
Lev Levanov, University of Helsinki
Alexander Plyusnin, University of Helsinki

20. Influenza Viruses 262
Dalius J. Briedis, McGill University
Alyson Kelvin, University of Calgary

21. Reoviruses 278
Kristen M. Ogden, Vanderbilt University
Terence S. Dermody, University of Pittsburgh School of Medicine

Section V: Small DNA Animal Viruses

22. Parvoviruses 292
Peter Beard, École Polytechnique Fédérale de Lausanne
Sarah Wootton, University of Guelph

23. Polyomaviruses 302
Nicholas H. Acheson, McGill University
James A. DeCaprio, Dana-Farber Cancer Institute, Harvard University

24. Papillomaviruses 318
Greg Matlashewski, McGill University
Lawrence Banks, International Centre for Genetic Engineering and Biotechnology, Trieste
Miranda Thomas, International Centre for Genetic Engineering and Biotechnology, Trieste

Section VI: Large DNA Animal Viruses

25. Adenoviruses 330
Philip Branton, McGill University
Richard C. Marcellus, McGill University
Luca D. Bertzbach, Leibniz Institute of Virology, Hamburg
Thomas Dobner, Leibniz Institute of Virology, Hamburg

26. Herpesviruses 344
Bernard Roizman, University of Chicago
Gabriella Campadelli-Fiume, University of Bologna
Richard Longnecker, Northwestern University
Bruce Banfield, Queens University
Craig McCormick, Dalhousie University

27. Poxviruses 366
Richard Condit, University of Florida
Matthew D. Gresseth, Medical University of South Carolina
Paula Traktman, Medical University of South Carolina

Section VII: Viruses with a Reverse Transcriptase

28. Retroviruses 382
Alan Cochrane, University of Toronto

29. Human Immunodeficiency Virus 394
Alan Cochrane, University of Toronto

30. Hepadnaviruses 406
Christopher D. Richardson, Dalhousie University
William Addison, University of Alberta D.
Lorne Tyrrell, University of Alberta

Section VIII: Viroids and Prions

31. Viroids and Hepatitis Delta Virus 420
Jean-Pierre Perreault, Université de Sherbrooke
Martin Pelchat, University of Ottawa
Charith Raj Adkar-Purushothama, Université de Sherbrooke

32. Prions 431
Dalius J. Briedis, McGill University
David Westaway, University of California, San Francisco

Section IX: Viruses of Plants, Algae, and Invertebrates

33. Cucumber Mosaic Virus 444
Marilyn J. Roossinck, Pennsylvania State College of Agricultural Sciences

34. Viruses of Algae and Mimivirus, a Giant Virus 457
Michael J. Allen, University of Exeter
William H. Wilson, Marine Biological Association, Plymouth
John A. Duffy, University of Exeter

35. Baculoviruses 478
Eric Carstens, Queens University
Robert L. Harrison, U.S. Department of Agriculture, Beltsville, Maryland

36. Viruses of Invertebrates 489
Peter Krell, University of Guelph

Section X: Host Defenses Against Virus Infection

37. Innate Immune Responses Against Virus Infection 506
Karen Mossman, McMaster University
John Hiscott, Istituto Pasteur-Fondazione Cenci Bolognetti, Rome
Alessandra Zevini, Istituto Pasteur-Fondazione Cenci Bolognetti, Rome

38. Adaptive Immune Responses to Virus Infection 527
Malcolm G. Baines, McGill University
Karen Mossman, McMaster University
Naglaa Shoukry, University of Montreal

Section XI: Medical Applications of Virology

39. Antiviral Vaccines 542
Brian Ward, McGill University
Hilary E. Hendin, McGill University

40. Antiviral Chemotherapy 562
Donald M. Coen, Harvard Medical School

41. Oncolytic Viruses 578
Vishnupriyan Kumar, Dalhousie University
Liang-Tzung Lin, Taipei Medical University
Shashi Gujar, Dalhousie University

42. Virus-Mediated Gene Therapy 586
Richard Peluso, Renovacor, Philadelphia
Christopher D. Richardson, Dalhousie University