Part I: Gynecologic Cytopathology
SECTION 1: OVERVIEW

4 Pap Test and Cervical Cancer Screening: History and Reporting Terminology
Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD
8 Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology
Michael J. Thrall, MD and Debora A. Smith, CT(ASCP)
10 Specimen Adequacy in Cervicovaginal Cytology
Dina R. Mody, MD and George G. Birdsong, MD

SECTION 2: BENIGN AND INFECTIOUS CONDITIONS

14 Normal Pap Test Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD
16 Infectious and Other Organisms in Pap Tests Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD
18 Nonneoplastic Findings, Mimics, and Artifacts
Ekene I. Okoye, MD and Dina R. Mody, MD

SECTION 3: SQUAMOUS CELLABNORMALITIES AND MIMICS

28 Low-Grade Squamous Intraepithelial Lesion and Mimics
Dina R. Mody, MD
30 High-Grade Squamous Intraepithelial Lesion and Mimics
Dina R. Mody, MD and Ekene I. Okoye, MD
34 Atypical Squamous Cells of Undetermined Significance
Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC and Dina R. Mody, MD
36 Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion
Dina R. Mody, MD and Nikolaos Chantziantoniou, PhD, ART(CSMLS), CFIAC
38 Squamous Cell Carcinoma of Cervix, Variants and Mimics
Dina R. Mody, MD

46 Endocervical Adenocarcinoma In Situ, Variants and Mimics
Dina R. Mody, MD
52 Endocervical Adenocarcinoma, Variants and Mimics
Dina R. Mody, MD
56 Adenocarcinoma, Gastric Type
Dina R. Mody, MD
58 Endometrial Cancers: Usual Types, Variants, and Mimics
Ekene I. Okoye, MD and Dina R. Mody, MD
64 Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS
Dina R. Mody, MD
70 Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy
Dina R. Mody, MD and Ekene I. Okoye, MD

74 Extrauterine Carcinomas and Presentations in
Cervicovaginal Cytology
Dina R. Mody, MD
76 Neuroendocrine Carcinoma of Cervix
Dina R. Mody, MD
78 Other Uncommon Malignancies in Cervicovaginal
Cytology
Dina R. Mody, MD

84 HPV and Other Molecular Testing in Gynecologic Cytology
Michael J. Thrall, MD

90 Directly Sampled Endometrial Cytology
Yuko Sugiyama, MD, PhD, FIAC and Dina R. Mody, MD

96 Anal Cytology
Michael J. Thrall, MD

Part II: Exfoliative Cytopathology

Specimen Types in Respiratory Cytology and Adequacy Criteria
Michael J. Thrall, MD
102 Benign and Reactive Changes
Michael J. Thrall, MD
106 PneumocystisPneumonia and Mimics
Michael J. Thrall, MD
108 Fungal Organisms in Respiratory Cytology
Michael J. Thrall, MD
Parasitic Organisms in Respiratory Cytology
Michael J. Thrall, MD
112 Viral Infections (Cytomegalovirus, Herpesvirus, and Others)
Michael J. Thrall, MD
114 Mycobacteria and Other Bacterial Infections
Michael J. Thrall, MD
116 Sarcoidosis and Other Immune-Related Conditions
Michael J. Thrall, MD
118 Pulmonary Alveolar Proteinosis and Mimics
Michael J. Thrall, MD
Miscellaneous Findings, Including Contaminants
Michael J. Thrall, MD
122 Adenocarcinoma
Michael J. Thrall, MD
126 Squamous Cell Carcinoma
Michael J. Thrall, MD
128 Small Cell Carcinoma
Michael J. Thrall, MD
Large Cell Neuroendocrine Carcinoma
Michael J. Thrall, MD
132 Carcinoid and Atypical Carcinoid
Michael J. Thrall, MD
134 Rare Benign and Low Malignant Potential Tumors
Michael J. Thrall, MD
136 Rare Malignant Tumors
Michael J. Thrall, MD
138 NUT Carcinoma
Michael J. Thrall, MD
139 SMARCA4-Deficient Undifferentiated Tumor
Michael J. Thrall, MD
Pulmonary Lymphoma
Michael J. Thrall, MD
142 Pulmonary Metastasis
Michael J. Thrall, MD

146 Specimen Types in Gastrointestinal Cytology and Normal Cellular Components
Blythe K. Gorman, MD
148 Parasitic Infections
Blythe K. Gorman, MD
Viral Infections
Blythe K. Gorman, MD
152 Esophagitis and Barrett Esophagus
Blythe K. Gorman, MD
154 Esophageal Adenocarcinoma
Blythe K. Gorman, MD
156 Esophageal Squamous Cell Carcinoma
Blythe K. Gorman, MD
158 Gastritis and Intestinal Metaplasia
Blythe K. Gorman, MD
Gastric Adenocarcinoma
Blythe K. Gorman, MD
162 Gastric Lymphoma
Blythe K. Gorman, MD
164 Ampulla/Bile Duct/Pancreatic Duct Reactive Changes
Blythe K. Gorman, MD
166 Ampulla/Bile Duct/Pancreatic Duct Adenocarcinoma
Blythe K. Gorman, MD
168 Colorectal Adenoma/Carcinoma
Blythe K. Gorman, MD
Neuroendocrine Tumor/Carcinoma
Blythe K. Gorman, MD
172 Spindle Cell Neoplasms of Gastrointestinal Tract, Including Gastrointestinal Stromal Tumors
Blythe K. Gorman, MD

176 Normal Cerebrospinal Fluid and Contamination by Normal Elements
Hidehiro Takei, MD
Infectious Meningitis
Hidehiro Takei, MD
182 Aseptic and Mollaret Meningitis
Hidehiro Takei, MD
184 Subarachnoid Hemorrhage
Hidehiro Takei, MD
186 Neurodegenerative Diseases
Hidehiro Takei, MD
188 Primary Brain Tumors
Hidehiro Takei, MD
Leukemia and Lymphoma
Hidehiro Takei, MD
192 Metastasis in Cerebrospinal Fluid
Hidehiro Takei, MD

196 Normal Cellular Components, Reactive Mesothelial Proliferations, and Reporting Terminology
Donna M. Coffey, MD and Michael J. Thrall, MD
Infectious Conditions
Donna M. Coffey, MD and Michael J. Thrall, MD
202 Autoimmune Diseases
Donna M. Coffey, MD and Michael J. Thrall, MD
204 Malignant Effusion, Mesothelioma
208 Malignant Effusion, Carcinomas 212 Malignant Effusion, Sarcomas

Donna M. Coffey, MD, Nour Sneige, MD, and Michael J. Thrall, MD

214 Lymphoid Effusions and Lymphomas
Donna M. Coffey, MD and Michael J. Thrall, MD

216 Primary Effusion Lymphoma
John M. Stewart, MD, PhD and Michael J. Thrall, MD

218 Endometriosis and Endosalpingiosis
Donna M. Coffey, MD, Nour Sneige, MD, and Michael J. Thrall, MD

220 Ovarian Neoplasms
Donna M. Coffey, MD and Michael J. Thrall, MD

222 Immunocytochemistry, Histochemistry, and Other Ancillary Techniques
Donna M. Coffey, MD and Michael J. Thrall, MD

228 Normal Urinary Cytology, Specimen Types, and Reporting Terminology
Michael J. Thrall, MD and Rose Anton, MD

232 Ileal Conduit Specimens
Rose Anton, MD and Michael J. Thrall, MD

234 Noninfectious Benign Conditions
Rose Anton, MD and Michael J. Thrall, MD

236 Infectious Benign Conditions
Rose Anton, MD and Michael J. Thrall, MD

238 Reactive Urothelial Changes
Rose Anton, MD and Michael J. Thrall, MD

240 Low-Grade Urothelial Lesions
Rose Anton, MD and Michael J. Thrall, MD

241 Atypical Urothelial Cells
Michael J. Thrall, MD

242 High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In Situ
Rose Anton, MD and Michael J. Thrall, MD

244 Squamous Cell Carcinoma of Urinary Bladder
Rose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD

246 Adenocarcinoma of Urinary Bladder
Rose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD

248 Other Malignancies in Urinary Cytology
Rose Anton, MD, Nour Sneige, MD, and Michael J. Thrall, MD

250 Renal Pelvic Cytology
Blythe K. Gorman, MD and Michael J. Thrall, MD

252 Ancillary Testing, UroVysion, and Others
Gene Landon, MD, Nancy P. Caraway, MD, and Michael J. Thrall, MD

Part III: Fine-Needle Aspiration, Superficial

256 Superficial Aspiration Technique
Rose Anton, MD and Dina R. Mody, MD

260 Ultrasound-Guided Thyroid Fine-Needle Aspiration
Paula J. Woodward, MD
266 Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy
Dina R. Mody, MD
268 Adenomatous (Benign Follicular) Nodule
Mojgan Amrikachi, MD and Dina R. Mody, MD
270 Chronic Lymphocytic/Hashimoto Thyroiditis
Mojgan Amrikachi, MD and Dina R. Mody, MD
272 Granulomatous Thyroiditis
Mojgan Amrikachi, MD and Dina R. Mody, MD
274 Graves Disease/Diffuse Toxic Goiter
Mukul K. Divatia, MD and Dina R. Mody, MD
275 Pigmented Thyroid Lesions and Crystals
Mukul K. Divatia, MD and Dina R. Mody, MD
276 Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance
Dina R. Mody, MD
280 Follicular Neoplasm/Suspicious for a Follicular Neoplasm
Dina R. Mody, MD
284 Follicular Neoplasm, Oncocytic (Hürthle Cell) Type
Mojgan Amrikachi, MD and Dina R. Mody, MD
286 Papillary Thyroid Carcinoma, Classic Subtype
Mojgan Amrikachi, MD and Dina R. Mody, MD
290 Papillary Thyroid Carcinoma Subtypes
Mojgan Amrikachi, MD and Dina R. Mody, MD
298 Medullary Thyroid Carcinoma
Mojgan Amrikachi, MD and Dina R. Mody, MD
302 Poorly Differentiated Thyroid Carcinoma
Susan L. Haley, MD and Dina R. Mody, MD
304 Anaplastic Thyroid Carcinoma
Susan L. Haley, MD and Dina R. Mody, MD
306 Thyroid Lymphoma
Susan L. Haley, MD and Dina R. Mody, MD
308 Metastatic Carcinoma to Thyroid
Susan L. Haley, MD and Dina R. Mody, MD
310 Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA
Mojgan Amrikachi, MD and Dina R. Mody, MD

318 Parathyroid Cyst, Adenoma, and Carcinoma Susan L. Haley, MD, Rose Anton, MD, and Dina R. Mody, MD

OVERVIEW
324 Lymph Node Aspiration: Indications, Techniques, and Reporting
Rose Anton, MD and Dina R. Mody, MD
326 FNA Sample Prep and Triage in Evaluating Suspected Lymphoma
John M. Stewart, MD, PhD and Savitri Krishnamurthy, MD

BENIGN, INFECTIOUS, AND REACTIVE HYPERPLASIA
328 Inflammatory and Reactive...