Development and evaluation of film coated ...

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Sprache: Englisch

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Beschreibung

The study is an attempt towards developing a formulation of an anti-estrogen drug, which belongs to non-steroidal aromatase inhibitor and which has in-vitro dissolution profile similar to that of reference product. Our target is to develop a dosage form similar to reference product for generic drug application to abbreviated new drug application (ANDA). Immediate drug delivery is required to alter the pharmacokinetics and pharmacodynamics of pharmacological active moieties by using physiological parameters inherent in the selected route of administration. It is also desirable to show rapid onset of action. In case of patient needing a quick action, conventional tablets are unable to release medicament rapidly. The drugs having long half-life and more bioavailability are beneficial for the formulation of immediate release dosage forms. Therefore, the present project involves the development of a formula for an orally administrable immediate release tablet of an anti-estrogen drug, letrozole which must be stable, bio-equivalent to reference listed drug product and has a reproducible and robust process of medication to prevent breast cancer relapse.

Über den Autor

O autor é um académico de profissão com mais de 24 anos de experiência em Instituições de Ensino Superior, mas continua a ser um laerner no centro.

Details

Erscheinungsjahr:	2019
Fachbereich:	Toxikologie
Genre:	Importe , Medizin
Rubrik:	Wissenschaften
Medium:	Taschenbuch
Inhalt:	124 S.
ISBN-13:	9786200114280
ISBN-10:	6200114285
Sprache:	Englisch
Ausstattung / Beilage:	Paperback
Einband:	Kartoniert / Broschiert
Autor:	Sharma, Upasana Gupta, Swati
Hersteller:	LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU:	LAP Lambert Academic Publishing, Brivibas Gatve 197, ?-1039 Riga, customerservice@vdm-vsg.de
Maße:	220 x 150 x 8 mm
Von/Mit:	Upasana Sharma (u. a.)
Erscheinungsdatum:	27.05.2019
Gewicht:	0,203 kg

Artikel-ID: 116826030

Über den Autor

O autor é um académico de profissão com mais de 24 anos de experiência em Instituições de Ensino Superior, mas continua a ser um laerner no centro.

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