Determination of the Antiretroviral Drug L...

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Sprache: Englisch

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Beschreibung

A solid-state iodide selective electrode with Ag2S-AgI adsorbed on graphite rod, recovered from a dry cell, was prepared and validated for its typical response characteristics with an objective to develop a potentiometric titration system for rapid measurements of Lamuvidine (LMV) in tablets used as an antiretroviral drug for Hepatis B and HIV patients. The partial validationexhibited typical response values of linear range of 10-6 to 10-1 M iodide and a slope 57.57 mV/decade which reasonably agreed with early data from our [...] basis of LMV determination is its oxidation by excess bromine generated from bromate-bromide mixture. The unreacted bromine oxidized the added excess iodide to iodine. The amount of bromine consumed by LMV, the basis of its determination, was determined by subtracting the back-titrated iodine with thiosulphate whose end-point was located potentiometrically with the solid state iodide selective electrode against a reference electrode. The iodometric back titration provided for the indirect determination of 1-30 mg LMV in turbid tablet test solutions.

Über den Autor

I am a highly enthusiastic professional always trying hard to fulfill my goals to grow professionally and spritually which is indispensable for the well being of human kind. born and grown up in a beautiful town Bahirdar, Ethiopia. Currently i am a lecturer in analytical chemistry,at one of the oldest universities in Ethiopia, Haremaya university.

Erscheinungsjahr:	2011
Genre:	Ratgeber , Sachbuch
Rubrik:	Ratgeber
Thema:	Briefe, Bewerbungen, Wiss. Arbeiten, Rhetorik
Medium:	Taschenbuch
Inhalt:	60 S.
ISBN-13:	9783846528778
ISBN-10:	3846528773
Sprache:	Englisch
Ausstattung / Beilage:	Paperback
Einband:	Kartoniert / Broschiert
Autor:	Hudie, Shemsia Mohamed Moges, Ghirma
Hersteller:	LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU:	BoD - Books on Demand, In de Tarpen 42, D-22848 Norderstedt, info@bod.de
Maße:	220 x 150 x 4 mm
Von/Mit:	Shemsia Mohamed Hudie (u. a.)
Erscheinungsdatum:	24.10.2011
Gewicht:	0,107 kg