T. D. Wilkins: Clostridium difficile | Buch

Cover: 9783540672913 | Clostridium difficile | T. D. Wilkins (u. a.) | Buch | ix | Englisch

Rückseite: 9783540672913 | Clostridium difficile | T. D. Wilkins (u. a.) | Buch | ix | Englisch

Dekorationsartikel gehören nicht zum Leistungsumfang.

Sprache: Englisch

134,95 €

inkl. MwSt.

Versandkostenfrei per Post / DHL

Lieferzeit 1-2 Wochen

Kategorien:

Beschreibung

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. Clostridium difficile toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.

Zusammenfassung

Includes supplementary material: [...]

Inhaltsverzeichnis

List of Contents.- Microbiology, Epidemiology and Diagnosis of Clostridium difficile Infection.- Genetics of Clostridium difficile Toxins.- Molecular Mode of Action of the Large Clostridial Cytotoxins.- Cytotoxic Effects of the Clostridium difficile Toxins.- Large Clostridial Cytotoxins as Tools in Cell Biology.- Pathogenesis and Clinical Manifestations of Clostridium difficile Diarrhea and Colitis.- Treatment of Clostridium difficile-Associated Diarrhea and Colitis.

Details

Erscheinungsjahr:	2000
Fachbereich:	Allgemeines
Genre:	Biologie , Mathematik , Medizin , Naturwissenschaften , Technik
Rubrik:	Naturwissenschaften & Technik
Thema:	Lexika
Medium:	Buch
Inhalt:	ix 150 S. 30 s/w Illustr.
ISBN-13:	9783540672913
ISBN-10:	3540672915
Sprache:	Englisch
Herstellernummer:	10664872
Einband:	Gebunden
Autor:	Aktories, K. Wilkins, T. D.
Redaktion:	Wilkins, T. D. Aktories, K.
Herausgeber:	K Aktories/T D Wilkins
Hersteller:	Springer-Verlag GmbH Springer Berlin Heidelberg
Verantwortliche Person für die EU:	Springer Verlag GmbH, Tiergartenstr. 17, D-69121 Heidelberg, juergen.hartmann@springer.com
Maße:	241 x 160 x 14 mm
Von/Mit:	T. D. Wilkins (u. a.)
Erscheinungsdatum:	06.07.2000
Gewicht:	0,412 kg