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Clarithromycin Resistant H. pylori among Dyspeptic Patients in Sudan
in Sudan
Taschenbuch von Nazar Wadedy
Sprache: Englisch

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Beschreibung
Helicobacter pylori is a gram-negative bacterium that forms the etiology of chronic gastritis and peptic ulcer disease. Infection with H. pylori can be effectively treated by the combination of a proton pump inhibitor in addition Clarithromycin and amoxicillin. Emergence of Clarithromycin resistant strains of was not well studied in Sudan. Clarithromycin is a macrolide that binds to the 23S rRNA components of the bacterial ribosome. Resistant strains emerge due to failure of such binding because of modification of the target site by point mutations in the peptidyl transferase region of domain V of the 23S rRNA. H. pylori contain two copies of the 23S rRNA gene8. Several points mutations have been reported that are associated with macrolide resistance, but the most common is A-G transitions at position 2143 (A2143G).
Helicobacter pylori is a gram-negative bacterium that forms the etiology of chronic gastritis and peptic ulcer disease. Infection with H. pylori can be effectively treated by the combination of a proton pump inhibitor in addition Clarithromycin and amoxicillin. Emergence of Clarithromycin resistant strains of was not well studied in Sudan. Clarithromycin is a macrolide that binds to the 23S rRNA components of the bacterial ribosome. Resistant strains emerge due to failure of such binding because of modification of the target site by point mutations in the peptidyl transferase region of domain V of the 23S rRNA. H. pylori contain two copies of the 23S rRNA gene8. Several points mutations have been reported that are associated with macrolide resistance, but the most common is A-G transitions at position 2143 (A2143G).
Über den Autor
Nazar. A. Osman, PhD on Medical Laboratory Science. Assistance professor of Medical Microbiology at Ahfad University for Women., Sudan .Have many research in field of Medical Microbiology and Human Biology.
Details
Erscheinungsjahr: 2012
Fachbereich: Allgemeines
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Thema: Lexika
Medium: Taschenbuch
Inhalt: 172 S.
ISBN-13: 9783846592168
ISBN-10: 3846592161
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Wadedy, Nazar
Hersteller: LAP LAMBERT Academic Publishing
Maße: 220 x 150 x 11 mm
Von/Mit: Nazar Wadedy
Erscheinungsdatum: 13.12.2012
Gewicht: 0,274 kg
Artikel-ID: 106121041
Über den Autor
Nazar. A. Osman, PhD on Medical Laboratory Science. Assistance professor of Medical Microbiology at Ahfad University for Women., Sudan .Have many research in field of Medical Microbiology and Human Biology.
Details
Erscheinungsjahr: 2012
Fachbereich: Allgemeines
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Thema: Lexika
Medium: Taschenbuch
Inhalt: 172 S.
ISBN-13: 9783846592168
ISBN-10: 3846592161
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Wadedy, Nazar
Hersteller: LAP LAMBERT Academic Publishing
Maße: 220 x 150 x 11 mm
Von/Mit: Nazar Wadedy
Erscheinungsdatum: 13.12.2012
Gewicht: 0,274 kg
Artikel-ID: 106121041
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