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Brahmi Ghrita: A Neuroprotective Polyherbal Formula for Brain Diseases
A novel study on neuroinflammation and neurodegeneration
Taschenbuch von Rakesh Kumar Banote
Sprache: Englisch

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Beschreibung
The anti-inflammatory effect of Brahmi Ghrita (BG) was investigated in rat hippocampus and cerebral cortex following ICV (Intracerebroventricular) infusion of Poly I:C by immunohistochemical studies. BG contains Bacopa monneri (Brahmi), Evolvulous alsinoids, Acorus calamus, Saussurea lappa and cow¿s ghee. After creating inflammatory condition by Poly I:C infusion directly into the rat brain ventricle, BG was fed orally to the normal animals. The effect of BG on inflammation of hippocampus and cerebral cortex was studied using immunohistochemical markers: Iba-1, OX-6 and GFAP. In this investigation, the anti-inflammatory effects of BG was clearly observed in the form of downregulation of the proliferation and activation of microglial cells as well as the suppression of MHC-II expression as compare to Poly I:C treated groups. In conclusion, the constituents of BG acted as a neuroprotective agent and may also be useful as a neuroprotective formula in several neurodegenerative diseases.
The anti-inflammatory effect of Brahmi Ghrita (BG) was investigated in rat hippocampus and cerebral cortex following ICV (Intracerebroventricular) infusion of Poly I:C by immunohistochemical studies. BG contains Bacopa monneri (Brahmi), Evolvulous alsinoids, Acorus calamus, Saussurea lappa and cow¿s ghee. After creating inflammatory condition by Poly I:C infusion directly into the rat brain ventricle, BG was fed orally to the normal animals. The effect of BG on inflammation of hippocampus and cerebral cortex was studied using immunohistochemical markers: Iba-1, OX-6 and GFAP. In this investigation, the anti-inflammatory effects of BG was clearly observed in the form of downregulation of the proliferation and activation of microglial cells as well as the suppression of MHC-II expression as compare to Poly I:C treated groups. In conclusion, the constituents of BG acted as a neuroprotective agent and may also be useful as a neuroprotective formula in several neurodegenerative diseases.
Über den Autor
Rakesh earned his Master¿s in Neuroscience from Jiwaji University, Gwalior, India. Currently he is working as a Junior Research Biologist at ZEPHASE Therapeutics, Institute of Life Science, University of Hyderabad (A.P.) India. His area of research interests are: Neuropharmacology, Neurobehavior biology and Neurotoxicology.
Details
Erscheinungsjahr: 2012
Fachbereich: Allgemeine Lexika
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Inhalt: 60 S.
ISBN-13: 9783844304077
ISBN-10: 384430407X
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Banote, Rakesh Kumar
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: LAP Lambert Academic Publishing, Brivibas Gatve 197, ?-1039 Riga, customerservice@vdm-vsg.de
Maße: 220 x 150 x 4 mm
Von/Mit: Rakesh Kumar Banote
Erscheinungsdatum: 01.06.2012
Gewicht: 0,107 kg
Artikel-ID: 106420777
Über den Autor
Rakesh earned his Master¿s in Neuroscience from Jiwaji University, Gwalior, India. Currently he is working as a Junior Research Biologist at ZEPHASE Therapeutics, Institute of Life Science, University of Hyderabad (A.P.) India. His area of research interests are: Neuropharmacology, Neurobehavior biology and Neurotoxicology.
Details
Erscheinungsjahr: 2012
Fachbereich: Allgemeine Lexika
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Inhalt: 60 S.
ISBN-13: 9783844304077
ISBN-10: 384430407X
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Banote, Rakesh Kumar
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: LAP Lambert Academic Publishing, Brivibas Gatve 197, ?-1039 Riga, customerservice@vdm-vsg.de
Maße: 220 x 150 x 4 mm
Von/Mit: Rakesh Kumar Banote
Erscheinungsdatum: 01.06.2012
Gewicht: 0,107 kg
Artikel-ID: 106420777
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