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Beschreibung
The knowledge of the structural, molecular, and functional biology of bone is essential for better comprehension of this tissue as a multicellular unit and a dynamic structure that can also act as an endocrine tissue, a function still poorly understood. In vitro and in vivo studies have demonstrated that bone cells respond to different factors and molecules, contributing to the better understanding of bone cells plasticity. Additionally, bone matrix integrins-dependent bone cells interactions are important for bone formation and resorption. Studies have addressed the importance of the lacuna-canalicular system and the pericellular fluid, by which osteocytes act as mechanosensors, for the adaptation of bone to mechanical forces. Hormones, cytokines, and factors that regulate bone cells activity, play a significant role in the bone histophysiology under normal and pathological conditions. Thus, such deeper understanding of the dynamic nature of bone tissue will certainly help to manage new therapeutic approaches to bone diseases and in various orthodontic treatment.
The knowledge of the structural, molecular, and functional biology of bone is essential for better comprehension of this tissue as a multicellular unit and a dynamic structure that can also act as an endocrine tissue, a function still poorly understood. In vitro and in vivo studies have demonstrated that bone cells respond to different factors and molecules, contributing to the better understanding of bone cells plasticity. Additionally, bone matrix integrins-dependent bone cells interactions are important for bone formation and resorption. Studies have addressed the importance of the lacuna-canalicular system and the pericellular fluid, by which osteocytes act as mechanosensors, for the adaptation of bone to mechanical forces. Hormones, cytokines, and factors that regulate bone cells activity, play a significant role in the bone histophysiology under normal and pathological conditions. Thus, such deeper understanding of the dynamic nature of bone tissue will certainly help to manage new therapeutic approaches to bone diseases and in various orthodontic treatment.
Über den Autor
A Dra. Soumyashree Biswal, estudante de pós-graduação do Departamento de Ortodontia e Ortopedia Dentofacial do Saraswati Dental College & Hospital, Lucknow, foi galardoada com uma medalha de ouro no BDSO Dr. Ragni Tandon, Professor e Diretor e o Dr. Kamlesh Singh, Professor, Departamento de Ortodontia e Ortopedia Facial, SDC&H, Lucknow têm inúmeras publicações em seu nome.
Details
Erscheinungsjahr: 2023
Fachbereich: Mund- und Kieferheilkunde
Genre: Importe, Medizin
Rubrik: Wissenschaften
Medium: Taschenbuch
ISBN-13: 9786207450992
ISBN-10: 620745099X
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Biswal, Soumyashree
Tandon, Ragni
Singh, Kamlesh
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de
Maße: 220 x 150 x 5 mm
Von/Mit: Soumyashree Biswal (u. a.)
Erscheinungsdatum: 08.12.2023
Gewicht: 0,125 kg
Artikel-ID: 128241404

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