PART I The Molecular Design of Life

SECTION 1 Biochemistry Helps Us Understand Our World

1. Biochemistry and the Unity of Life

2. Water, Weak Bonds, and the Generation of Order Out of Chaos

SECTION 2 Protein Composition and Structure

3. Amino Acids

4. Protein Three-Dimensional Structure

5. Techniques in Protein Biochemistry

SECTION 3 Basic Concepts and Kinetics of Enzymes

6. Basic Concepts of Enzyme Action

7. Kinetics and Regulation

8. Mechanisms and Inhibitors

9. Hemoglobin, an Allosteric Protein

SECTION 4 Carbohydrates and Lipids

10. Carbohydrates

11. Lipids

SECTION 5 Cell Membranes, Channels, Pumps, and Receptors

12. Membrane Structure and Function

13. Signal-Transduction Pathways

PART II Transducing and Storing Energy

SECTION 6 Basic Concepts and Design of Metabolism

14. Digestion: Turning a Meal into Cellular Biochemicals

15. Metabolism: Basic Concepts and Design

SECTION 7 Glycolysis and Gluconeogenesis

16. Glycolysis

17. Gluconeogenesis

SECTION 8 The Citric Acid Cycle

18. Preparation for the Cycle

19. Harvesting Electrons from the Cycle

SECTION 9 Oxidative Phosphorylation

20. The Electron-Transport Chain

21. The Proton-Motive Force

SECTION 10 The Light Reactions of Photosynthesis and the Calvin Cycle

22. The Light Reactions

23. The Calvin Cycle

SECTION 11 Glycogen Metabolism and the Pentose Phosphate Pathway

24. Glycogen Degradation

25. Glycogen Synthesis

26.The Pentose Phosphate Pathway

SECTION 12 Fatty Acid and Lipid Metabolism

27. Fatty Acid Degradation

28. Fatty Acid Synthesis

29. Lipid Synthesis: Storage Lipids, Phospholipids, and Cholesterol

SECTION 13 The Metabolism of Nitrogen-Containing Molecules

30. Amino Acid Degradation and the Urea Cycle

31. Amino Acid Synthesis

32. Nucleotide Metabolism

PART III Synthesizing the Molecules of Life

SECTION 14 Nucleic Acid Structure and DNA Replication

33. The Structure of Informational Macromolecules: DNA and RNA

34. DNA Replication

35. DNA Repair and Recombination

SECTION 15 RNA Synthesis, Processing, and Regulation

36. RNA Synthesis and Regulation in Bacteria

37. Gene Expression in Eukaryotes

38. RNA Processing in Eukaryotes

SECTION 16 Protein Synthesis and Recombinant DNA Techniques

39. The Genetic Code

40. The Mechanism of Protein Synthesis

41. Recombinant DNA Techniques