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Cover: 9780521857000 | Algebraic Statistics for Computational Biology | B. Sturmfels | Buch
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Algebraic Statistics for Computational Biology
Buch von B. Sturmfels
Sprache: Englisch

126,95 €*

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Lieferzeit 2-3 Wochen

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Beschreibung
The quantitative analysis of biological sequence data is based on methods from statistics coupled with efficient algorithms from computer science. Algebra provides a framework for unifying many of the seemingly disparate techniques used by computational biologists. This book introduces this framework and describes tools for designing new algorithms for exact, accurate results. These are applied to biological problems such as aligning genomes, finding genes and constructing phylogenies. As the first book in the exciting and dynamic area, it will be welcomed as a text for self-study or for course use.
The quantitative analysis of biological sequence data is based on methods from statistics coupled with efficient algorithms from computer science. Algebra provides a framework for unifying many of the seemingly disparate techniques used by computational biologists. This book introduces this framework and describes tools for designing new algorithms for exact, accurate results. These are applied to biological problems such as aligning genomes, finding genes and constructing phylogenies. As the first book in the exciting and dynamic area, it will be welcomed as a text for self-study or for course use.
Inhaltsverzeichnis
Preface; Part I. Introduction to the Four Themes: 1. Statistics L. Pachter and B. Sturmfels; 2. Computation L. Pachter and B. Sturmfels; 3. Algebra L. Pachter and B. Sturmfels; 4. Biology L. Pachter and B. Sturmfels; Part II. Studies on the Four Themes: 5. Parametric inference R. Mihaescu; 6. Polytope propagation on graphs M. Joswig; 7. Parametric sequence alignment C. Dewey and K. Woods; 8. Bounds for optimal sequence alignment S. Elizalde; 9. Inference functions S. Elizalde; 10. Geometry of Markov chains E. Kuo; 11. Equations defining hidden Markov models N. Bray and J. Morton; 12. The EM algorithm for hidden Markov models I. B. Hallgrímsdóttir, A. Milowski and J. Yu; 13. Homology mapping with Markov random fields A. Caspi; 14. Mutagenetic tree models N. Beerenwinkel and M. Drton; 15. Catalog of small trees M. Casanellas, L. Garcia and S. Sullivant; 16. The strand symmetric model M. Casanellas and S. Sullivant; 17. Extending statistical models from trees to splits graphs D. Bryant; 18. Small trees and generalized neighbor-joining M. Contois and D. Levy; 19. Tree construction using Singular Value Decomposition N. Eriksson; 20. Applications of interval methods to phylogenetics R. Sainudiin and R. Yoshida; 21. Analysis of point mutations in vertebrate genomes J. Al-Aidroos and S. Snir; 22. Ultra-conserved elements in vertebrate genomes M. Drton, N. Eriksson and G. Leung; Index.
Details
Erscheinungsjahr: 2013
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Buch
Seiten: 434
ISBN-13: 9780521857000
ISBN-10: 0521857007
Sprache: Englisch
Ausstattung / Beilage: HC gerader Rücken kaschiert
Einband: Gebunden
Redaktion: Sturmfels, B.
Hersteller: Cambridge University Press
Maße: 260 x 183 x 28 mm
Von/Mit: B. Sturmfels
Erscheinungsdatum: 15.11.2013
Gewicht: 1,008 kg
preigu-id: 102249842
Inhaltsverzeichnis
Preface; Part I. Introduction to the Four Themes: 1. Statistics L. Pachter and B. Sturmfels; 2. Computation L. Pachter and B. Sturmfels; 3. Algebra L. Pachter and B. Sturmfels; 4. Biology L. Pachter and B. Sturmfels; Part II. Studies on the Four Themes: 5. Parametric inference R. Mihaescu; 6. Polytope propagation on graphs M. Joswig; 7. Parametric sequence alignment C. Dewey and K. Woods; 8. Bounds for optimal sequence alignment S. Elizalde; 9. Inference functions S. Elizalde; 10. Geometry of Markov chains E. Kuo; 11. Equations defining hidden Markov models N. Bray and J. Morton; 12. The EM algorithm for hidden Markov models I. B. Hallgrímsdóttir, A. Milowski and J. Yu; 13. Homology mapping with Markov random fields A. Caspi; 14. Mutagenetic tree models N. Beerenwinkel and M. Drton; 15. Catalog of small trees M. Casanellas, L. Garcia and S. Sullivant; 16. The strand symmetric model M. Casanellas and S. Sullivant; 17. Extending statistical models from trees to splits graphs D. Bryant; 18. Small trees and generalized neighbor-joining M. Contois and D. Levy; 19. Tree construction using Singular Value Decomposition N. Eriksson; 20. Applications of interval methods to phylogenetics R. Sainudiin and R. Yoshida; 21. Analysis of point mutations in vertebrate genomes J. Al-Aidroos and S. Snir; 22. Ultra-conserved elements in vertebrate genomes M. Drton, N. Eriksson and G. Leung; Index.
Details
Erscheinungsjahr: 2013
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Buch
Seiten: 434
ISBN-13: 9780521857000
ISBN-10: 0521857007
Sprache: Englisch
Ausstattung / Beilage: HC gerader Rücken kaschiert
Einband: Gebunden
Redaktion: Sturmfels, B.
Hersteller: Cambridge University Press
Maße: 260 x 183 x 28 mm
Von/Mit: B. Sturmfels
Erscheinungsdatum: 15.11.2013
Gewicht: 1,008 kg
preigu-id: 102249842
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